Meningococcal Vaccines: A Technological Revolution

نویسندگان

چکیده

The sneaky meningococcus is a bacterium that can cause terrible disease. Development of an effective vaccine has been extremely difficult. Meningococcal vaccines developed in the 1990s are based on bacterial capsule, shield protects bacteria and used to instruct our body combat this These work against four types meningococcus: A, C, W, Y. However, they do not B. Scientists had invent completely new way make vaccines, reading DNA search for protective components. With approach, named reverse vaccinology, three components were discovered: NadA, NHBA, fHbp. When combined with fourth component (PorA), form 4CMenB vaccine. This reduced meningococcal disease infants by 75% UK. Today, children all around world.

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ژورنال

عنوان ژورنال: Frontiers for Young Minds

سال: 2021

ISSN: ['2296-6846']

DOI: https://doi.org/10.3389/frym.2020.560305